Novel inhibitors of phosphorylation independent activity of GRK2 modulate cAMP signaling
Abstract G protein‐coupled receptors kinase 2 (GRK2) plays a major role in receptor regulation and, as a consequence, in cell biology and physiology. GRK2‐mediated receptor desensitization is performed by its kinase domain, which exerts receptor phosphorylation promoting G protein uncoupling and the...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2022-04-01
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| Serier: | Pharmacology Research & Perspectives |
| Fag: | |
| Online adgang: | https://doi.org/10.1002/prp2.913 |
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