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Protective effects of liraglutide on hypercholesterolemia-associated atherosclerosis involve attenuation of endothelial-monocyte adhesion through down-regulating the LOX-1/NF-κB signaling pathway

Abstract To investigate the impact of liraglutide (LIR) on experimental hypercholesterolemia-associated atherosclerosis and endothelial-monocyte adhesion, as well as elucidate the involvement of lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1)/NF-κB signaling pathway in this process....

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Principais autores: Aiping Wu, Ying Wu, Meiyan Song, Wen Chen, Kaizu Xu, Meifang Wu, Liming Lin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-07-01
Serier:Scientific Reports
Fag:
Liraglutide
Endothelial cells
Adhesion
Lectin-like ox-LDL receptor 1
Nuclear factor-κB
Online adgang:https://doi.org/10.1038/s41598-025-13014-2
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