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Garcinol prevents oxidative stress-induced bone loss and dysfunction of BMSCs through NRF2-antioxidant signaling

Abstract There are multiple published data showing that excessive oxidative stress contributes to bone loss and even bone tissue damage, and it is also correlated with the pathophysiology of bone degenerative diseases, including osteoporosis (OP). Garcinol, a polyisoprenylated benzophenone derivativ...

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Autors principals: Jilong Zou, Hongjun Chen, Xinming Fan, Zhenrui Qiu, Jiale Zhang, Jiabing Sun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2024-02-01
Col·lecció:Cell Death Discovery
Accés en línia:https://doi.org/10.1038/s41420-024-01855-1
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