Poly (ADP-Ribose) Polymerase Inhibitor, ABT888, Improved Cisplatin Effect in Human Oral Cell Carcinoma

Cisplatin is one of the chemotherapeutic drugs used for the management of oral carcinoma, in which combined therapies are estimated to exert superior therapeutic efficacy compared with monotherapy. It is known that poly(ADP-ribosyl)ation is implicated in a multiplicity of cellular activities, such a...

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Autori principali:	Irene Paterniti, Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Marzia Mare, Raffella Giuffrida, Cristina Colarossi, Marco Portelli, Salvatore Cuzzocrea, Emanuela Esposito
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-07-01
Serie:	Biomedicines
Soggetti:	oral cancer human oral cell carcinoma cisplatin PARP inhibitors (PARPi) veliparib (ABT888) apoptosis
Accesso online:	https://www.mdpi.com/2227-9059/9/7/771
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