The SDF-1α/CXCR4 axis regulates chondrocyte mitochondrial dynamics via the ERK/AMPKα pathway
Abstract Mitochondrial quality control is crucial for maintaining chondrocyte homeostasis, and mitochondrial dysfunction is a key contributor to osteoarthritic (OA) pathogenesis. Reports have indicated that the level of SDF-1α increases during the progression of OA; however, its effects on mitochond...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2026-03-01
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| coleção: | Cell Communication and Signaling |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12964-026-02827-x |
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