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LOMA: A fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens

<p>Abstract</p> <p>Background</p> <p>Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utilize random primers rather than specific primers for the RT-PCR step, bias inherent in random PCR...

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Autori principali: Lee Wah, Wong Christopher W, Leong Wan, Miller Lance D, Sung Wing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2008-09-01
Serie:BMC Bioinformatics
Accesso online:http://www.biomedcentral.com/1471-2105/9/368
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