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Airway Bacteria Quantification Using Polymerase Chain Reaction Combined with Neutrophil and Eosinophil Counts Identifies Distinct COPD Endotypes

Background: Chronic obstructive pulmonary disease (COPD) inflammatory endotypes are associated with different airway microbiomes. We used quantitative polymerase chain reaction (qPCR) analysis of sputum samples to establish the bacterial load upper limit in healthy controls; these values determined...

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Principais autores: Augusta Beech, Simon Lea, Jian Li, Natalie Jackson, Alex Mulvanny, Dave Singh
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-09-01
סדרה:Biomedicines
נושאים:
chronic obstructive pulmonary disease
inflammatory endotypes
<i>Haemophilus influenzae</i>
eosinophil
eosinophilic inflammation
neutrophil
גישה מקוונת:https://www.mdpi.com/2227-9059/9/10/1337
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