Airway Bacteria Quantification Using Polymerase Chain Reaction Combined with Neutrophil and Eosinophil Counts Identifies Distinct COPD Endotypes

Background: Chronic obstructive pulmonary disease (COPD) inflammatory endotypes are associated with different airway microbiomes. We used quantitative polymerase chain reaction (qPCR) analysis of sputum samples to establish the bacterial load upper limit in healthy controls; these values determined...

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Detalhes bibliográficos

Principais autores:	Augusta Beech, Simon Lea, Jian Li, Natalie Jackson, Alex Mulvanny, Dave Singh
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-09-01
Colecção:	Biomedicines
Assuntos:	chronic obstructive pulmonary disease inflammatory endotypes <i>Haemophilus influenzae</i> eosinophil eosinophilic inflammation neutrophil
Acesso em linha:	https://www.mdpi.com/2227-9059/9/10/1337
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