Mendelian Randomization Analyses Suggest Childhood Body Size Indirectly Influences End Points From Across the Cardiovascular Disease Spectrum Through Adult Body Size

Background Obesity is associated with long‐term health consequences including cardiovascular disease. Separating the independent effects of childhood and adulthood obesity on cardiovascular disease risk is challenging as children with obesity typically remain overweight throughout the lifecourse. Me...

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Hlavní autoři:	Grace M. Power, Jessica Tyrrell, Timothy M. Frayling, George Davey Smith, Tom G. Richardson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2021-09-01
Edice:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Témata:	cardiovascular disease genetic epidemiology lifecourse Mendelian randomization obesity
On-line přístup:	https://www.ahajournals.org/doi/10.1161/JAHA.121.021503
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