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Infrared free electron laser-irradiated polyleucine does not exert aggregates-induced aversive effects on mouse brain

Polyglutamine (polyQ) diseases are devastating neurological disorders that cannot be effectively treated. Repeat-associated non-AUG (RAN) translation has been documented in transcripts in polyQ diseases. RAN products include proteins with polyleucine (polyL) tracts. Similar to polyQ, polyL tends to...

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Principais autores: Ayaka Mori, Taichi Shiroishi, Jun Fujioka, Takashi Nakajima, Shinichi Mitsui, Hinaho Suginoma, Yohei Kakuta, Heishun Zen, Kazuhiro Nakamura
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-06-01
Colecção:Brain Disorders
Assuntos:
Aggregation
FEL irradiation
Infrared
Polyleucine
Neurodegeneration
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666459324000222
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