Phenome-wide association of APOE alleles in the All of Us Research ProgramResearch in context

Summary: Background: Apolipoprotein E (APOE) variation is associated with altered lipid metabolism, as well as cardiovascular and neurodegenerative disease. Prior studies are largely limited to European ancestry populations and differential risk by sex and ancestry has not been widely evaluated. Me...

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Detalhes bibliográficos

Principais autores:	Ehsan Khajouei, Valentina Ghisays, Ignazio S. Piras, Kiana L. Martinez, Anthony T. Vicenti, Marcus Naymik, Preston Ngo, Tam C. Tran, Joshua C. Denny, Travis J. Wheeler, Matthew J. Huentelman, Eric M. Reiman, Jason H. Karnes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-07-01
coleção:	EBioMedicine
Assuntos:	Apolipoprotein E Phenome-wide association study Health disparities Alzheimer’s disease Hypercholesterolaemia
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352396425002129
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