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In Vitro and In Vivo Attenuation of Vesicular Stomatitis Virus (VSV) by Phosphoprotein Deletion.

Vesicular stomatitis virus (VSV) is highly immunogenic and able to stimulate both innate and adaptive immune responses. However, its ability to induce adverse effects has held back the use of VSV as a potential vaccine vector. In this study we developed VSV-ΔP, a safe yet potent replication-defectiv...

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Библиографические подробности
Главные авторы: Phonphimon Wongthida, Juggragarn Jengarn, Jaraspim Narkpuk, Pongpisid Koonyosying, Kanjana Srisutthisamphan, Asawin Wanitchang, Pornsawan Leaungwutiwong, Samaporn Teeravechyan, Anan Jongkaewwattana
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2016-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4912100?pdf=render
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