A Single V672F Substitution in the Spike Protein of Field-Isolated PEDV Promotes Cell–Cell Fusion and Replication in VeroE6 Cells

While porcine epidemic diarrhea virus (PEDV) infects and replicates in enterocytes lining villi of neonatal piglets with high efficiency, naturally isolated variants typically grow poorly in established cell lines, unless adapted by multiple passages. Cells infected with most cell-adapted PEDVs usua...

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Detalhes bibliográficos

Principais autores:	Asawin Wanitchang, Janya Saenboonrueng, Challika Kaewborisuth, Kanjana Srisutthisamphan, Anan Jongkaewwattana
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2019-03-01
coleção:	Viruses
Assuntos:	PEDV spike cell–cell fusion syncytium chimeric proteins receptor preference
Acesso em linha:	https://www.mdpi.com/1999-4915/11/3/282
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