Two-step interphase microtubule disassembly aids spindle morphogenesis

Abstract Background Entry into mitosis triggers profound changes in cell shape and cytoskeletal organisation. Here, by studying microtubule remodelling in human flat mitotic cells, we identify a two-step process of interphase microtubule disassembly. Results First, a microtubule-stabilising protein,...

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Autors principals:	Nunu Mchedlishvili, Helen K. Matthews, Adam Corrigan, Buzz Baum
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-01-01
Col·lecció:	BMC Biology
Matèries:	Mitosis Spindle assembly Nuclear envelope breakdown Ensconsin/MAP7 Microtubules Multipolar spindle
Accés en línia:	http://link.springer.com/article/10.1186/s12915-017-0478-z
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