New role of endoplasmic reticulum chaperones in regulating metaplasia during tumorigenesis

Metaplasia is emerging as a key process in tumorigenesis. We discovered that 2 essential endoplasmic reticulum (ER) chaperones, 78-kilodalton glucose-regulated protein (GRP78) and 94-kilodalton glucose-regulated protein (GRP94) have a role in metaplasia. Grp78 haploinsufficiency in the mouse pancrea...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jieli Shen, Daisy F. Rangel, Dat Ha, Amy S. Lee
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2017-11-01
Цуврал:	Molecular & Cellular Oncology
Нөхцлүүд:	er chaperone grp78 grp94 metaplasia mouse models pancreatic cancer
Онлайн хандалт:	http://dx.doi.org/10.1080/23723556.2017.1345350
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!