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Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation

Cyclophilin D (CypD) promotes opening of the mitochondrial permeability transition pore (MPTP) which plays a key role in both cell physiology and pathology. It is, therefore, beneficial for cells to tightly regulate CypD and MPTP but little is known about such regulation. We have reported before tha...

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Autors principals: Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2022-05-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/75023
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