Somatic mutational profiles and germline polygenic risk scores in human cancer
Abstract Background The mutational profile of cancer reflects the activity of the mutagenic processes which have been operative throughout the lineage of the cancer cell. These processes leave characteristic profiles of somatic mutations called mutational signatures. Mutational signatures, including...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2022-02-01
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| Serie: | Genome Medicine |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13073-022-01016-y |
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