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Efficacy and safety of hypofractionated radiotherapy combined with temozolomide in patients with newly diagnosed glioblastoma with poor prognosis: a single-center retrospective analysis

BackgroundThe optimal management for newly diagnosed glioblastoma (GBM) patients with poor prognostic features, such as RPA class IV-VI or rapid early progression, remains debated. This study evaluated the efficacy and safety of postoperative hypofractionated radiotherapy (HFRT) with concurrent temo...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Fangmeng Fu, Li Ma, Fengming Lan, Peng Chen, Teng Zou, Ling Lei, Renba Liang, Manyi Zhu, Jianghu Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-05-01
Schriftenreihe:Frontiers in Oncology
Schlagworte:
efficacy
glioblastoma
hypofractionated radiotherapy
poor prognosis
temozolomide
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fonc.2026.1782296/full
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