Efficacy and safety of hypofractionated radiotherapy combined with temozolomide in patients with newly diagnosed glioblastoma with poor prognosis: a single-center retrospective analysis

BackgroundThe optimal management for newly diagnosed glioblastoma (GBM) patients with poor prognostic features, such as RPA class IV-VI or rapid early progression, remains debated. This study evaluated the efficacy and safety of postoperative hypofractionated radiotherapy (HFRT) with concurrent temo...

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Autors principals:	Fangmeng Fu, Li Ma, Fengming Lan, Peng Chen, Teng Zou, Ling Lei, Renba Liang, Manyi Zhu, Jianghu Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-05-01
Col·lecció:	Frontiers in Oncology
Matèries:	efficacy glioblastoma hypofractionated radiotherapy poor prognosis temozolomide
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1782296/full
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