The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation.

<h4>Background</h4>The regulatory subunit (R) of cAMP-dependent protein kinase (PKA) is a modular flexible protein that responds with large conformational changes to the binding of the effector cAMP. Considering its highly dynamic nature, the protein is rather stable. We studied the thermal denatura...

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Autors principals:	Khanh K Dao, Angel L Pey, Anja Underhaug Gjerde, Knut Teigen, In-Ja L Byeon, Stein O Døskeland, Angela M Gronenborn, Aurora Martinez
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2011-03-01
Col·lecció:	PLoS ONE
Accés en línia:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21394209/pdf/?tool=EBI
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