Development of novel lipoplex formulation methodologies to improve large-scale transient transfection for lentiviral vector manufacture

Large-scale transient transfection has advanced significantly over the last 20 years, enabling the effective production of a diverse range of biopharmaceutical products, including viral vectors. However, a number of challenges specifically related to transfection reagent stability and transfection c...

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Ngā kaituhi matua:	Thomas Williams-Fegredo, Lee Davies, Carol Knevelman, Kyriacos Mitrophanous, James Miskin, Qasim A. Rafiq
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2024-06-01
Rangatū:	Molecular Therapy: Methods & Clinical Development
Ngā marau:	lentiviral vector transient transfection transient gene expression HEK293T cationic liposomes lipoplexes
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2329050124000767
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