Selective cyclooxygenase-2 inhibitor celecoxib could sensitize B-cell-originated lymphoma cell lines to epirubicin via down-regulation of MDR-1 mRNA and Bcl-2 mRNA expression
Background and purpose: It has been demonstrated that cyclooxygenase-2 (COX-2) is overexpressed in some subtypes of non-Hodgkin’s lymphoma (NHL), and COX-2 correlates with the expression of P-glycoprotein and Bcl-2, which may contribute to chemotherapy-resistance in NHL. The purpose of this study wa...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Editorial Office of China Oncology
2015-08-01
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| Schriftenreihe: | Zhongguo aizheng zazhi |
| Schlagworte: | |
| Online-Zugang: | http://www.china-oncology.com/thesisDetails#10.3969/j.issn.1007-3969.2015.06.005 |
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