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Evaluation of mTOR, NFκB and BCL-2 Inhibitor Activity In Vitro in Karpas 1106P, a Primary Mediastinal B-Cell Lymphoma Cell Line

<b>Introduction</b>: PMBCL is an aggressive type of lymphoma characterized by high heterogeneity in clinical, molecular, and genetic features. In PMBCL, disturbances in the NFkB pathway and deregulation of BCL-2 and mTOR family proteins are observed, which may contribute to impaired apoptosis. There...

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Bibliografski detalji
Glavni autori: Agata Majchrzak, Sylwia Mańka, Barbara Cebula-Obrzut, Paweł Robak, Damian Mikulski, Magdalena Witkowska
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2026-03-01
Serija:Hematology Reports
Teme:
Online pristup:https://www.mdpi.com/2038-8330/18/2/25
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