Evaluation of mTOR, NFκB and BCL-2 Inhibitor Activity In Vitro in Karpas 1106P, a Primary Mediastinal B-Cell Lymphoma Cell Line

<b>Introduction</b>: PMBCL is an aggressive type of lymphoma characterized by high heterogeneity in clinical, molecular, and genetic features. In PMBCL, disturbances in the NFkB pathway and deregulation of BCL-2 and mTOR family proteins are observed, which may contribute to impaired apoptosis. There...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Agata Majchrzak, Sylwia Mańka, Barbara Cebula-Obrzut, Paweł Robak, Damian Mikulski, Magdalena Witkowska
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
Colecção:	Hematology Reports
Assuntos:	mTOR inhibitors NFkB inhibitors BCL-2 inhibitors primary mediastinal B-cell lymphoma
Acesso em linha:	https://www.mdpi.com/2038-8330/18/2/25
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!