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Nedd4-2–dependent Ubiquitination Potentiates the Inhibition of Human NHE3 by Cholera Toxin and Enteropathogenic Escherichia coliSummary

Background & Aims: Diarrhea is one of the most common illnesses and is often caused by bacterial infection. Recently, we have shown that human Na+/H+ exchanger NHE3 (hNHE3), but not non-human NHE3s, interacts with the E3 ubiquitin ligase Nedd4-2. We hypothesize that this property of hNHE3 contri...

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Principais autores: Kayte A. Jenkin, Yiran Han, Songbai Lin, Peijian He, C. Chris Yun
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2022-01-01
Serija:Cellular and Molecular Gastroenterology and Hepatology
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2352345X2100240X
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