Hematological phenotypes in GATA2 deficiency syndrome arise from aging, maladaptation to proliferation, and somatic events
Abstract: The GATA2 transcription factor is a pivotal regulator of hematopoiesis. Disruptions in the GATA2 gene drive severe hematologic abnormalities and are associated with an increased risk of myelodysplastic syndromes and acute myeloid leukemia; however, the mechanisms underlying the pathophysio...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2025-06-01
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| Seria: | Blood Advances |
| Dostęp online: | http://www.sciencedirect.com/science/article/pii/S2473952925001892 |
| Etykiety: |
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