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Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective

Abstract Status epilepticus (SE) in humans is characterized by prolonged convulsive seizures that are generalized and often difficult to control. The current antiseizure drugs (ASDs) aim to stop seizures quickly enough to prevent the SE-induced brain inflammation, injury, and long-term sequelae. How...

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Bibliografiske detaljer
Principais autores: Nelufar Yasmen, Madison N. Sluter, Lexiao Li, Ying Yu, Jianxiong Jiang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-01-01
Serier:Molecular Brain
Fag:
Online adgang:https://doi.org/10.1186/s13041-023-01008-y
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