Immune humanization of immunodeficient mice using diagnostic bone marrow aspirates from carcinoma patients.

Tumor xenografts in immunodeficient mice, while routinely used in cancer research, preclude studying interactions of immune and cancer cells or, if humanized by allogeneic immune cells, are of limited use for tumor-immunological questions. Here, we explore a novel way to generate cancer models with...

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Egile Nagusiak:	Melanie Werner-Klein, Judith Proske, Christian Werno, Katharina Schneider, Hans-Stefan Hofmann, Brigitte Rack, Stefan Buchholz, Roman Ganzer, Andreas Blana, Birgit Seelbach-Göbel, Ulrich Nitsche, Daniela N Männel, Christoph A Klein
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Public Library of Science (PLoS) 2014-01-01
Saila:	PLoS ONE
Sarrera elektronikoa:	http://europepmc.org/articles/PMC4022674?pdf=render
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