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Pro-Opiomelanocortin and Melanocortin Receptor 3 and 4 Mutations in Genetic Obesity

Genetic obesity results from loss-of-function mutations, including those affecting the leptin–melanocortin system, which regulates body weight. Pro-opiomelanocortin (POMC)-derived neurohormones act as ligands for melanocortin receptors (MCRs), regulating the leptin–melanocortin pathway through prote...

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Autors principals: Tulin Yanik, Seyda Tugce Durhan
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-02-01
Col·lecció:Biomolecules
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Accés en línia:https://www.mdpi.com/2218-273X/15/2/209
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