Pro-Opiomelanocortin and Melanocortin Receptor 3 and 4 Mutations in Genetic Obesity
Genetic obesity results from loss-of-function mutations, including those affecting the leptin–melanocortin system, which regulates body weight. Pro-opiomelanocortin (POMC)-derived neurohormones act as ligands for melanocortin receptors (MCRs), regulating the leptin–melanocortin pathway through prote...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI AG
2025-02-01
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| Serier: | Biomolecules |
| Fag: | |
| Online adgang: | https://www.mdpi.com/2218-273X/15/2/209 |
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