Inhibition of Activated Coagulation Factor XII by the Phosphodiesterase-4 Inhibitor Roflumilast: In Vitro and In Silico Studies
Background: This study aimed to evaluate the effects of selected phosphodiesterase-4 inhibitors (PDE-4 inhibitors)—roflumilast, ibudilast, and crisaborole—on the activity of blood coagulation factor XII (FXII). In the intrinsic coagulation pathway, FXII is known to initiate the ka...
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| Huvudupphov: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
IMR Press
2025-05-01
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| Serie: | Frontiers in Bioscience-Landmark |
| Ämnen: | |
| Länkar: | https://www.imrpress.com/journal/FBL/30/5/10.31083/FBL38395 |
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