Multimericity Amplifies the Synergy of BCR and TLR4 for B Cell Activation and Antibody Class Switching

Sustained signaling through the B cell antigen receptor (BCR) is thought to occur only when antigen(s) crosslink or disperse multiple BCR units, such as by multimeric antigens found on the surfaces of viruses or bacteria. B cell-intrinsic Toll-like receptor (TLR) signaling synergizes with the BCR to...

詳細記述

書誌詳細

主要な著者:	Egest J. Pone, Jenny E. Hernandez-Davies, Sharon Jan, Emily Silzel, Philip L. Felgner, D. Huw Davies
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2022-05-01
シリーズ:	Frontiers in Immunology
主題:	multimericity B cells class switching B cell receptor (BCR) Toll-like receptor (TLR) synergy
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.882502/full
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