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Pharmacokinetic and Pharmacodynamic Considerations in Relation to Calcineurin Usage in Elderly Kidney Transplant Recipients

This review summarizes how possible age-related changes in tacrolimus and cyclosporine pharmacokinetics and pharmacodynamics may influence drug dosing and monitoring in the elderly, and highlights how micro-sampling may be useful in this cohort in the future. Advancing biological age leads to physio...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Amelia R. Cossart, Nicole M. Isbel, Carla Scuderi, Scott B. Campbell, Christine E. Staatz
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2021-04-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2021.635165/full
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