The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord

Understanding the cellular and molecular basis of selective vulnerability has been challenging, especially for motor neuron diseases. Developing drugs that improve the health of neurons that display selective vulnerability relies on <i>in vivo</i> cell-based models and quantitative readout measures...

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Principais autores:	Baris Genc, Oge Gozutok, Nuran Kocak, P. Hande Ozdinler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-02-01
coleção:	Cells
Assuntos:	corticospinal motor neuron als misfolded sod1 motor neurons selective vulnerability
Acesso em linha:	https://www.mdpi.com/2073-4409/9/2/502
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