Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis

Cytokines, demyelination and neuroaxonal degeneration in the central nervous system are pivotal elements implicated in the pathogenesis of multiple sclerosis (MS) and its nonclinical model of experimental autoimmune encephalomyelitis (EAE). Phycocyanobilin (PCB), a chromophore of the biliprotein C-P...

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Principais autores:	Javier Marín-Prida, Nancy Pavón-Fuentes, Nielsen Lagumersindez-Denis, Hanlet Camacho-Rodríguez, Ana Margarita García-Soca, Rocío de la Caridad Sarduy-Chávez, Érica Leandro Marciano Vieira, Juliana Carvalho-Tavares, Viviana Falcón-Cama, Julio Raúl Fernández-Massó, Ignacio Hernández-González, Gillian Martínez-Donato, Gerardo Guillén-Nieto, Eduardo Pentón-Arias, Mauro Martins Teixeira, Giselle Pentón-Rol
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2022-11-01
丛编:	Frontiers in Immunology
主题:	interferon-β proinflammatory cytokines remyelination antioxidants experimental autoimmune encephalomyelitis multiple sclerosis
在线阅读:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036200/full
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