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MOF-associated complexes ensure stem cell identity and Xist repression

Histone acetyl transferases (HATs) play distinct roles in many cellular processes and are frequently misregulated in cancers. Here, we study the regulatory potential of MYST1-(MOF)-containing MSL and NSL complexes in mouse embryonic stem cells (ESCs) and neuronal progenitors. We find that both compl...

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Guardat en:
Autors principals: Tomasz Chelmicki, Friederike Dündar, Matthew James Turley, Tasneem Khanam, Tugce Aktas, Fidel Ramírez, Anne-Valerie Gendrel, Patrick Rudolf Wright, Pavankumar Videm, Rolf Backofen, Edith Heard, Thomas Manke, Asifa Akhtar
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2014-05-01
Col·lecció:eLife
Matèries:
D. melanogaster
epigenetic
chromatin
transcription
acetylation
X inactivation
Accés en línia:https://elifesciences.org/articles/02024
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