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Path-based quantification of activation and repression in Boolean models using BooLEVARD

Abstract Boolean models are a powerful resource for studying dynamic processes of biological systems. However, their inherent discrete nature limits their ability to capture continuous aspects of signal transduction, such as signal strength or protein activation levels. Although existing tools provi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Marco Fariñas, Eirini Tsirvouli, John Zobolas, Tero Aittokallio, Åsmund Flobak, Kaisa Lehti
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Portfolio 2025-11-01
Σειρά:npj Systems Biology and Applications
Διαθέσιμο Online:https://doi.org/10.1038/s41540-025-00605-y
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