External signals regulate continuous transcriptional states in hematopoietic stem cells

Hematopoietic stem cells (HSCs) must ensure adequate blood cell production following distinct external stressors. A comprehensive understanding of in vivo heterogeneity and specificity of HSC responses to external stimuli is currently lacking. We performed single-cell RNA sequencing (scRNA-Seq) on f...

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Principais autores:	Eva M Fast, Audrey Sporrij, Margot Manning, Edroaldo Lummertz Rocha, Song Yang, Yi Zhou, Jimin Guo, Ninib Baryawno, Nikolaos Barkas, David Scadden, Fernando Camargo, Leonard I Zon
格式:	Artigo
語言:	Inglês
出版:	eLife Sciences Publications Ltd 2021-12-01
叢編:	eLife
主題:	chromatin stem cell niche blood interferons prostaglandins growth factors
在線閱讀:	https://elifesciences.org/articles/66512
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