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Intracerebroventricular Administration of 192IgG-Saporin Alters Expression of Microglia-Associated Genes in the Dorsal But Not Ventral Hippocampus

One of important aspects of development of Alzheimer’s disease is degeneration of septal cholinergic neurons that innervate the hippocampus. We took advantage of widely used model of cholinergic deficit in the hippocampus, intracerebroventricular administration of 192IgG-saporin (Ig-saporin), to ana...

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Bibliografiska uppgifter
Huvudupphov: Yulia V. Dobryakova, Artem Kasianov, Maria I. Zaichenko, Mikhail Y. Stepanichev, Ekaterina A. Chesnokova, Petr M. Kolosov, Vladimir A. Markevich, Alexey P. Bolshakov
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2018-01-01
Serie:Frontiers in Molecular Neuroscience
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Länkar:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00429/full
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