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From acute tubular injury to tubular repair and chronic kidney diseases – KIM-1 as a promising biomarker for predicting renal tubular pathology

Kidney Injury Molecule-1 (KIM-1) has emerged as a significant biomarker and mechanistic player in kidney pathology, particularly in acute kidney injury (AKI). Normally absent in healthy kidney proximal tubules, KIM-1 becomes upregulated specifically along the proximal tubule cells' surface in respon...

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Principais autores: Ping L. Zhang, Ming-Lin Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-01-01
coleção:Current Research in Physiology
Assuntos:
Acute kidney injury
Tubular repair
Kidney injury molecule-1
Tubular dedifferentiation
Chronic kidney disease
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2665944125000148
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