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Targeting MCL1 by UMI-77 to induce mitophagy alleviates renal tubular epithelial cells injury in acute kidney injury

Abstract Acute kidney injury (AKI) is a common clinical disease with complex pathophysiological processes and with high morbidity and mortality. Severe mitochondrial damages, such as mitochondrial swelling and fragmentation, disruption of membrane integrity, and broken or absent cristae, were observ...

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Xehetasun bibliografikoak
Egile Nagusiak: Xiaoyu Li, Zixian Li, Yongming Chen, Hongluan Wu, Yonghan Liu, Zhennan Ye, Qingqing Yang, Haicha Hou, Junfeng Hao, Ruigao Song, Huafeng Liu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-12-01
Saila:Scientific Reports
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-34083-3
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