Expansion of CD4⁺CD25⁺helper T cells without regulatory function in smoking and COPD

<p>Abstract</p> <p>Background</p> <p>Regulatory T cells have been implicated in the pathogenesis of COPD by the increased expression of CD25 on helper T cells along with enhanced intracellular expression of FoxP3 and low/absent CD127 expression on the cell surface.</p> <p>Method</p> <p>Regulatory T...

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Hauptverfasser:	Bucht Anders, Behndig Annelie F, Pourazar Jamshid, Roos-Engstrand Ester, Blomberg Anders
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2011-06-01
Schriftenreihe:	Respiratory Research
Schlagworte:	Bronchoalveolar lavage BAL CD25<sup>bright</sup> CD127 FoxP3 lymphocyte subsets
Online-Zugang:	http://respiratory-research.com/content/12/1/74
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