Capturing cell‐fate decisions from the molecular signatures of a receptor‐dependent signaling response

Abstract We examined responses of the B‐cell antigen receptor‐dependent intracellular signaling network to targeted perturbations induced through siRNA‐mediated depletion of select signaling intermediates. The constituent nodes displayed graded sensitivities, which resulted from the differential eff...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Dhiraj Kumar, Ravichandran Srikanth, Helena Ahlfors, Riitta Lahesmaa, Kanury V S Rao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Springer Nature 2007-12-01
Schriftenreihe:	Molecular Systems Biology
Schlagworte:	B‐cell antigen receptor cellular responses intracellular signaling
Online-Zugang:	https://doi.org/10.1038/msb4100197
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!