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Capturing cell‐fate decisions from the molecular signatures of a receptor‐dependent signaling response

Abstract We examined responses of the B‐cell antigen receptor‐dependent intracellular signaling network to targeted perturbations induced through siRNA‐mediated depletion of select signaling intermediates. The constituent nodes displayed graded sensitivities, which resulted from the differential eff...

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Bibliografiske detaljer
Principais autores: Dhiraj Kumar, Ravichandran Srikanth, Helena Ahlfors, Riitta Lahesmaa, Kanury V S Rao
Format: Artigo
Sprog:Inglês
Udgivet: Springer Nature 2007-12-01
Serier:Molecular Systems Biology
Fag:
Online adgang:https://doi.org/10.1038/msb4100197
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