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Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study

IntroductionOvarian cancer has been difficult to cure due to acquired or intrinsic resistance and therefore, newer or more effective drugs/approaches are needed for a successful treatment in the clinic. Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive ox...

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Principais autores: Kaylie I. Kirkwood-Donelson, Alan K. Jarmusch, Carl D. Bortner, Bruce Alex Merrick, Birandra K. Sinha
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2025-01-01
Serija:Frontiers in Molecular Biosciences
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Online dostop:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1520876/full
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