Coq4 deficiency induces placental vascular development defects through FSP1/CoQ10 axis-mediated endothelial ferroptosis
IntroductionCoenzyme Q10 (CoQ10), a critical electron carrier in mitochondrial respiratory chains, is essential for cellular energy metabolism. Ubiquinone biosynthesis protein 4 homolog (Coq4), a rate-limiting enzyme in CoQ10 biosynthesis, is indispensable for embryonic development. However, the mec...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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Frontiers Media S.A.
2026-03-01
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| Colección: | Frontiers in Cell and Developmental Biology |
| Materias: | |
| Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fcell.2026.1774201/full |
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