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Coq4 deficiency induces placental vascular development defects through FSP1/CoQ10 axis-mediated endothelial ferroptosis

IntroductionCoenzyme Q10 (CoQ10), a critical electron carrier in mitochondrial respiratory chains, is essential for cellular energy metabolism. Ubiquinone biosynthesis protein 4 homolog (Coq4), a rate-limiting enzyme in CoQ10 biosynthesis, is indispensable for embryonic development. However, the mec...

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Rui Chen, Sikun Wang, Xueke He, Zhanbiao Wang, Miao Jiang
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2026-03-01
Sraith:Frontiers in Cell and Developmental Biology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fcell.2026.1774201/full
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