Down-regulation of the Nucleotide Excision Repair gene <it>XPG </it>as a new mechanism of drug resistance in human and murine cancer cells
<p>Abstract</p> <p>Background</p> <p>Drug resistance is one of the major obstacles limiting the activity of anticancer agents. Activation of DNA repair mechanism often accounts for increase resistance to cancer chemotherapy.</p> <p>Results</p> <p>We present evidence that nemorubicin, a doxorubicin d...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2010-09-01
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| Schriftenreihe: | Molecular Cancer |
| Online-Zugang: | http://www.molecular-cancer.com/content/9/1/259 |
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