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Characterization of Novel SARM1 Inhibitors for the Treatment of Chemotherapy-Induced Peripheral Neuropathy

Background: Sterile α and Toll/IL-1 receptor motif-containing 1 (SARM1) is a central regulator of programmed axon death and a crucial nicotinamide adenine dinucleotide (NAD+) hydrolase (NADase) in mammalian tissues, hydrolyzing NAD+ and playing an important role in cellular NAD+ recycling. Abnormal...

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Bibliografiske detaljer
Principais autores: Jiayu Chen, Hao Li
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-09-01
Serier:Biomedicines
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Online adgang:https://www.mdpi.com/2227-9059/12/9/2123
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