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Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer

Abstract Background An important component of the RAS signalling pathway, the RAS p21 oncogene, is frequently hyperactivated in breast cancer. Its expression in tumor tissue has been linked to poor clinical outcome. This study was designed to evaluate the clinical relevance of RAS p21 levels in peri...

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Principais autores: Malgorzata Banys-Paluchowski, Tanja Fehm, Wolfgang Janni, Bahriye Aktas, Peter A. Fasching, Sabine Kasimir-Bauer, Karin Milde-Langosch, Klaus Pantel, Brigitte Rack, Sabine Riethdorf, Erich-Franz Solomayer, Isabell Witzel, Volkmar Müller
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-05-01
Serier:BMC Cancer
Fag:
Breast cancer
RAS p21
RAS
Circulating tumor cell
Survival
Biomarker
Online adgang:http://link.springer.com/article/10.1186/s12885-018-4282-0
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